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Altered metabolism in cancer

Under stress, the body releases a flood of hormones like cortisol, which may deplete melanocyte reserves, hastening the premature graying of hair

10.1038/s41392-023-01588-0 48 GenchiG.LauriaG.CatalanoA.CarocciA.SinicropiM

If the immune cell is not responsive (e.g., proliferates or produces cytokines), it has become tolerant and the cytokines have not prevented tolerance induction