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It is important to note that in BRCA1-deficient mammary cells, activation of NRF2 via small interfering RNA inhibition of KEAP1 rescued the survival defect linked with loss of BRCA1 and caused ROS levels restoration, indicating that this mechanism is important (237, 240)

Membrane-Initiated estrogen, androgen, and progesterone receptor signaling in health and disease

To minimize muscle and brown fat uptake in the case of 18 F-FDG imaging, animals were kept anesthetized under warming lights for a 20-min period after injection