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In clinical chemistry testing, various GGT iso(en)zymes have been observed in electrophoretic separation and have been investigated to improve diagnostic accuracy [79]

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LRRK2 gene trigger lysosomal dysfunction and abnormal cellular response to membrane damage, leading to vesicular transport dysfunction, neuroinflammation, accumulation of alpha-synuclein, mitochondrial dysfunction and ciliary loss, ultimately leading to PD ( 4.2.2 Function of curcumin in PD Up to now, the research on curcumin in the treatment of PD has been mainly conducted at the molecular level and in mouse models