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Pluvicto is a targeted radioligand therapy for adult patients who have already undergone other anti-cancer treatments

[30] Side effects [edit] Folinic acid should not be administered intrathecally

In this work, we develop a peptide-ferriporphyrin conjugate with tumour microenvironment specific activation for improved tumor penetration and endocytosis, which enables effective inhibition of GPX4 due to the assembly enhanced binding (AEB) effect, ultimately improving its anticancer activity via ferroptosis (Fig

MERRF affects multiple systems and typically presents with myoclonus as the initial symptom, followed by generalized seizures, ataxia, fatigue, motor intolerance, and dementia