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Additionally, SOD converts superoxide anions into hydrogen peroxide, which subsequently acts as a substrate for catalase (Rahman, 2007)

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Counteracting leaky gut syndrome, via increased tight junction protein ZO-1 expression and transepithelial resistance [37], would avoid a shift of fluid and proteins from the intravascular to the extravascular space and thus prevent an increase in intra-abdominal pressure [27]

Treatment combining with ACTH, antiseizure medications, and vitamin B12 in these patients has shown improvments in EEG features and imaging manifestations, leading to a reduction in seizures