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[42] Low maternal vitamin B 12 , defined as serum concentration less than 148 pmol/L, increases the risk of miscarriage, preterm birth and newborn low birth weight

It is usually done in conjunction with the 30-Day Low Histamine Diet, and continued for about 3 months or longer if needed (i.e., with celiac or IBD the damage is likely high)

PPIs and H2 blockers can interfere with absorption of vitamin B12 from food: stomach acid shakes loose the vitamin B12 in food, making it easier to absorb into the blood

To overcome this, samples are typically tested at a large dilution to reduce matrix interference and ensure reliable recovery and detection in compliance with USP