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In experimental studies, MEL also influenced autophagy processes and phosphorylation of mTOR (mammalian target of rapamicin), which is a common, highly conserved serine/threonine kinase that binds to raptor or riptor and other proteins, forming mTORC1 and mTORC2 complexes in turn (264)

Aebi S, Assereto R et al

Elevated levels of reactive oxygen species (ROS) damage lipids, proteins, and nucleic acids in germ and Sertoli cells 7

Synthetic OSC derivatives and efflux/anti-biofilm activity - Recent medicinal chemistry work on stabilized sulfonyl and sulfoxide analogues shows promising in vitro potency against multidrug-resistant strains, with activity against efflux systems and biofilms in vitro and in select animal models