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These findings suggest that mitochondrial DNA methylation, especially in the CYB gene, could serve as a potential biomarker for NIHL

This possibility warrants future investigation and may inform the development of strategies aimed at improving host resilience to infection and tissue damage

1 For some, the dose, frequency and way vitamin B12 replacement is given may need to be adjusted or changed for it to work properly 1 the efficacy and costeffectiveness of oral treatment in wider population-based settings has yet to be established

When to stop or modify protocols Discontinue or modify protocols if symptoms worsen progressively, if new neurological symptoms develop, if allergic reactions occur, or if significant side effects emerge