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263,264 Additionally, optimizing the synthetic route to increase the overall yield, minimize costs, and mitigate the environmental impact is crucial

In contrast, we observed an increase basal coronary blood flow, which is in accordance with observations in humans with diabetes and CKD [35, 43, 50], but also patients with HFpEF in general [1] and is likely to be explained by the hearts heightened metabolic and oxygen demands imposed by elevated cardiac after- and/or preload [2]

J Biol Chem (1999) 274:1390814

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