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The target polynucleotide of a CRISPER complex can be any polynucleotide endogenous or exogenous to the eukaryotic cell

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Abbreviations: Ct = threshold cycles, Cre = Cre recombinase-mediated DNA recombination, eWAT = epididymal white adipose tissue, iWAT = inguinal white adipose tissue, MA = mature adipocytes, ND = non-detectable