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Older adults often have lower levels of stomach acid, which is needed to release B12 during digestion

Dose-response of oridonin on hepatic cytochromes P450 mRNA expression and activities in mice

Moreover, infants with an increased colonization of Firmicutes and a decreased colonization of Bacteroidetes (corresponding to an increased Firmicutes -to- Bacteroidetes ratio), or a decreased colonization of Proteobacteria and Bifidobacteria are shown to be at increased risk of developing food allergies (188191)