melanotic macule oral mucosa Pigmented Lesions of the Simple cryosurgical treatment of the

Beyond this main pathway, recycling via the ascorbate glutathione cycle, involving enzymes like MDHAR (Monodehydroascorbate Reductase) and DHAR (Dehydroascorbate Reductase), is crucial for maintaining the reduced pool of AsA by regenerating it from its oxidized forms, thus influencing the final vitamin C content in the ripe fruit as shown in Figure 4 ( Figure 4 Recent advances in molecular biology have provided powerful tools to dissect and manipulate this biosynthetic network

Crit Rev Food Sci Nutr 60(4):684694

doi: 10.3389/fcimb.2025.1673512 Received 26 July 2025 Revised 29 October 2025 Accepted 14 November 2025 Published 27 February 2026 Volume 15 - 2025 Edited by Soumyadev Sarkar, Arizona State University, United States Reviewed by Yoshihiko Tanaka, Fukuoka Dental College, Japan Chiara Scapoli, University of Ferrara, Italy Narjess Bostanghadiri, Tehran University of Medical Sciences, Iran Updates Copyright 2026 Gan, Chen, Zheng, Long, Cheng, Sulaiman and Huang

Wiley-VCH, Weinheim