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Methods: The signals of Tildrakizumab-associated ADRs were quantified using disproportionality analyses such as the reporting odds ratio (ROR), the proportional reporting ratio (PRR), the Bayesian confidence propagation neural network (BCPNN), and the multiitem gamma Poisson shrinker (MGPS) algorithms

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At lower, sub-toxic concentrations, sulforaphane increased NRF2-mediated antioxidant defenses, ultimately enhancing neuronal survival in cell culture models driven by oxidative and inflammatory insults (Table 2) (Vauzour et al., 2010