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CRISPR-Cas9-mediated genome editing has successfully generated Brassica varieties with significantly increased glucoraphanin accumulation by modulating key genes in the pathway, including MYB28, AOP2, and BCAT4 (27, 96, 107)

Machado DE, Berardo PT, Palmero CY, Nasciutti LE (2010) Higher expression of vascular endothelial growth factor (VEGF) and its receptor VEGFR-2 (Flk-1) and metalloproteinase-9 (MMP-9) in a rat model of peritoneal endometriosis is similar to cancer diseases

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10.1016/j.ophtha.2014.05.013 5