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For the study, which was published in February in the Annals of Neurology , researchers recruited 231 healthy older people without dementia or mild cognitive impairment (which is considered a precursor to dementia)

adding B12 (.5 mcg) reduced homocysteine an additional 7%.(7) B12 Brain Research Studies and Possible Benefits Most of the evidence supporting B12 as a nootropic suggests failing to get enough Vitamin B12 can negatively impact the brain