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Loss of GPX4 led to neurodegeneration and reduction of PV+ interneurons (Nahar et al., 2021), which are sensitive to oxidative stress (Wirth et al., 2010)

Staying hydrated, eating a protein-rich meal before drinking, and pacing yourself can help mitigate these age-related shifts

Especially now, in the era of innovative therapies, analyses are available indicating that intensive lipid-lowering therapy, especially combination therapy with the use of PCSK9 inhibitors, may translate into a highly significant reduction in the risk of patients with multibed disease, and the more advanced the disease (more beds involved), the greater the benefits