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In all experiments, the simultaneous reaction of reduction of disulfide bonds and derivatization of the thiol groups was stopped by adding 50 L of 3 mol/L PCA

The increase in circulating homocysteine related to impaired homocysteine metabolism may favor the accretion of a pro-oxidant environment by increasing concentrations of free radicals, by maintaining metal ions in their reduced state suitable for the Fenton reaction, and by changing the redox status of intra- and extracellular thiol groups and, hence, the intracellular redox potential (Mansoor et al, 1993a

The improvement in energy metabolism in raspberries is likely related to the generation of ROS, which are by-products of the respiratory chain and activate the expression of genes involved in ROS neutralization as well as DNA protection from damage (PARP-2)

Folate status, genomic DNA hypomethylation, and risk of colorectal adenoma and cancer: a case control study