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doi: 10.3389/fphar.2023.1191290 Received 22 March 2023 Accepted 28 July 2023 Published 08 August 2023 Volume 14 - 2023 Edited by Yusof Kamisah, Universiti Kebangaan Malaysia, Malaysia Reviewed by Patrick Orlando, Marche Polytechnic University, Italy Hana Rauchov, Academy of Sciences of the Czech Republic (ASCR), Czechia Iain Hargreaves, Liverpool John Moores University, United Kingdom Updates Copyright 2023 Dabbaghi Varnousfaderani, Musazadeh, Ghalichi, Kavyani, Razmjouei, Faghfouri, Ahrabi, Seyyed Shoura and Dehghan

No evidence of genotoxic activity was found in either assay

The therapeutic effect is entirely PepT1-dependent

Acknowledgements Financial support is acknowledged from: the Ministero dell'Istruzione, dell'Universit e della Ricerca (Progetti di Rilevante Interesse Nazionale PRIN 2017), the Universit degli Studi di Salerno (FARB 2017), the SPRING cluster (REBIOCHEM research project CTN01_00063_49393), the Regione Campania for the FT-ICR mass spectrometer facility (POR CAMPANIA FESR 2007/2013 O.O.2.1, CUP B46D14002660009), the Farma-BioNet (CUP B25C13000230007) and the Centro di Tecnologie Integrate per la Salute for the 600 MHz NMR facility (CITIS, project PONa3_00138)