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This represents the maximum potential EGR activity and is referred to as stimulated activity

Results 6-Paradol-treated rats showed improved muscular coordination in grip-strength, rotarod, and open-field tests and reduced histopathological damage

Macrophages with the G2019S mutation showed a significant increase in LTF relative to WT, and macrophages nucleofected with Lrrk2 anti-sense oligonucleotide (ASO) to cause Lrrk2 KD showed a significant reduction in LTF