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It was found that a 23-fold -synuclein overexpression in hippocampal and ventral midbrain neurons impeded synaptic vesicle release [116] while -synuclein knock-out mice displayed stronger release of DA upon stimulus [117]

Large-scale randomized controlled trials are urgently needed to establish safe lipid thresholds and optimize therapeutic strategies

Whole blood samples were collected into EDTA-coated tubes, and hematological parameters, including red blood cell count (RBC), hemoglobin (HGB), hematocrit (HCT), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC) were measured using the automatic biochemical analyzer (Shenzhen Myriad Biomedical Electronics Co, China)