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Hollier embraced transparency, doggedly responding to practically every one of the 2,000 queries and suggestions left on their crowdfunding page

Total protein was extracted with a combination of RIPA buffer (Sigma Aldrich, US) and a protease inhibitor cocktail (Roche, Shanghai, CN) per the manufacturers instructions

and a homozygous pathogenic mutation (4 points)

Autism spectrum disorder (ASD) is an extremely heterogeneous condition characterized by delays in reciprocal social interaction and communication skills, stereotyped behaviors, and a narrowed range of interests and limited activities