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Further research into pharmacokinetics, pharmacodynamics and optimal delivery strategies is necessary for successful clinical application

In light of the above concerns, establishing a proper IGF-1 DES dosage protocol is of paramount importance to any researcher wishing to study the compound

Polymer nanoparticles, such as those made from PLGA (poly(lactic-co-glycolic acid)), offer additional benefits, including the ability to modify the surface properties to target specific receptors on the BBB [270]

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