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Description

Inhibition of cyclooxygenase-2 (COX-2) with celecoxib significantly reduced PGE2, enhanced IFN- production and NO release, and increased phagocytosis of MTB by macrophages (97)

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No long-term or combination-specific safety data exist

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However, non-individualized tumor vaccines do not induce immune responses against autologous tumors owing to the high heterogeneity of tumor cells

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TRPV4 has been reported to be stimulated by citric acid solution (Buday et al., 2017

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