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doi: 10.3892/ijmm 505 MikeczAVKonstantinovKBuchwaldDSGeraceLTanEM

Keywords: A and oxidative damage, Alzheimer disease and lipid peroxidation and protein oxidation, Alzheimer disease and translational approaches, Down syndrome and Alzheimer disease and oxidative stress, oxidative stress and energy dysmetabolism Abstract Alzheimer disease (AD) is associated with multiple etiologies and pathological mechanisms, among which oxidative stress (OS) appears as a major determinant

10.1111/bph.13847 26 IsraelY.KarahanianE.EzquerF.MoralesP.EzquerM.Rivera-MezaM.et al

Inflammation is primarily triggered by the NF-B signaling pathway, which regulates proinflammatory genes such as ALOX5 and PTGS2, responsible for encoding enzymes like 5-lipoxygenase (5-LOX) and cyclooxygenase-2 (COX-2)