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At this time, Fe 3+ is reduced to divalent iron ions (Fe 2+ ) through the Steap3 (six- transmembrane epithelial antigen of the prostate), and then under the mediation of Transferrin Receptor-1(TFR-1), Fe 2+ is released from the endosome to the cytoplasm, and part of it is stored in unstable iron tanks

Rationale for using high-dose multiple dietary antioxidants as an adjunct to radiation therapy and chemotherapy

A reduction of nitric oxide generation lowers the risk of damage to the S-nitrosylation of glyceraldehyde-3-phosphate dehydrogenase (GAPDH), reduces ROS generation, and increases cell existence (Muronetz et al., 2017)

L., Uribe, C