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For example, nanoparticles leverage the enhanced permeability and retention (EPR) effect to accumulate in inflamed synovium, while stimuli-responsive systems release drugs in response to specific triggers, achieving a reduction in inflammation in preclinical models (10)

They also enhance the production of brain-derived neurotrophic factor (BDNF), which supports neuron health and cognitive function

Integrin beta1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs

Cigarette smoke impairs elastin resynthesis in lungs of hamsters with elastase-induced emphysema