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This N-terminal tyrosine modification making it technically Tyr-hGH Fragment 177-191 distinguishes the aod 9604 5mg research peptide from unmodified HGH Fragment 176-191 and contributes to its stability profile in laboratory conditions

The desired C2/3-diamino-group may be introduced via a two-step sequence involving an amination of C2-chloro- group with, for example, ammonia and reduction of C3-nitro group (via, e.g., hydrogenation) to give the precursor 16