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Plant adaptogens-history and future perspectives

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Ferritinophagy is medicated by adaptor NCOA4 through autophagic degradation of ferritin, causing the release of iron from lysosome to cytosol [28]

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Unlike other cell death pathways, ferroptosis involves the accumulation of oxidized lipids in cell membranes, which GPx4 counters by directly reducing these hydroperoxides to stable alcohols

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Balakrishnan et al., 2022)

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