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[PubMed: 22238382] 239

BPC-157 operates mainly through growth hormone receptor upregulation in connective tissue, NO-dependent angiogenic and cytoprotective signalling, FAK-paxillin pathway activation, and neurotransmitter system modulation , producing particularly pronounced effects on gastrointestinal cytoprotection, tendon-to-bone healing, and CNS neuroprotection alongside its broader tissue repair biology