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Rheumatoid arthritis synovial fibroblasts (RASFs) also have been extensively implicated in the pathogenesis of RA via secretion of pro-inflammatory factor and damage of articular [5]

The obtained serum samples were stored in a freezer at -80C until testing

In vitro studies using endothelial cell models have demonstrated effects on fibroblast migration rates, endothelial cell tube formation in angiogenesis assays, and cytoprotective mechanisms in cell culture models exposed to oxidative and chemical stressors