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10.1016/S0014-5793(02)03167-8 93 WilsonJ

Marazziti D, Baroni S, Picchetti M, Landi P, Silvestri S, Vatteroni E, Catena Dell'Osso M

While the above evidence indicates that the mitochondrial apoptotic pathway promotes cell death, recent provocative evidence has shown that the intrinsic apoptosis pathway mediates the pro-longevity response to mitochondrial ROS in Caenorhabditis elegans by triggering a unique pattern of gene expression that modulates stress sensitivity and promotes survival (Yee et al., 2014)