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2021 Jul;328:12435

& van Lieshout, L

Mesenchymal stem cells as a promising cell source for integration in novel in vitro models

This promotes a potent pro-inflammatory gene expression profile, enhancing glycolysis and the production of IL-1, thereby exacerbating chronic inflammation ( 3.2.2 Lactate and acidic microenvironment Excessive glycolysis, a consequence of failed OXPHOS, results in massive lactate production