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While the concept is in line with improving the key pathobiological defect in neurodegeneration (locus coeruleus degeneration, reduced noradrenergic innervation and decreased L-lactate production), further developments are needed to bring the proposal to a feasible clinical outcome

Similarly, the bioavailability of these compounds, which is influenced by their formulation and delivery systems, remains a critical challenge that limits their therapeutic efficacy

CCT8 promotes cell migration and tumor metastasis in lung adenocarcinomas

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