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Although most of the potential therapies reviewed here, particularly those for preventive use, have shown no effect on the anticancer activity of chemotherapeutic drugs in cancer cell lines or in tumor bearing animals, newly developed preventive and/or treatment strategy should be considered for translation into clinical practice

While studies have shown that VSMCs express the VLDL receptor and various scavenger receptors, (145,147,148) data showing that these cells robustly load with CE, (147) similar to macrophages via these mechanisms is lacking

This combined strategy can work better than using either compound alone, especially during times of physical demands, mental stress, or environmental challenges

The research revealed that the HCC model's glutaminolysis might be disrupted by the miR192/204HOTTIP axis, suggesting GLS1 as a putative downstream target