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105 , 106 Toroidal-Pore Model In the Toroidal-pore model (Figure 2C), AMPs also originally bind to the cell membrane through electrostatic attraction and then induce continuous bending of the lipid monolayer with the hydrophilic group of AMPs interacting with the hydrophilic head of the cell membrane and then spiral insertion into the cell membrane, forming transmembrane pores

During periods of strenuous or prolonged exercise, there is increased demand for energy

How these changes are related to the specific pattern of Piezo1 activity remains unclear (Ivkovic et al., 2022