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Acute neurodegenerationneurotrauma, stroke, autoimmune diseases and infection Acute traumatic lesions of the CNS trigger neurological and cognitive symptoms directly linked to the death of neural cellsparticularly neurons and oligodendrocytesdestroying both information-processing units and the connectome

Under normal conditions, glutathione is predominantly present in its reduced form, with only a small proportion present in its fully oxidized state [20]

PMC Research Status: NAD+ and its precursors (NMN, NR) are subjects of active preclinical and investigational human research

doi: 10.2165/00003495-200262040-00010 71 de HaanLDudek-HodgeCVerhoevenYDenysD