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Methylation genes tell us genetic predisposition but do not tell us phenotypic expression, which can be modulated by nutrient levels, gut health, toxic load, and use of methylation inhibitors (such as various drugs like PPIs, birth control pills, antibiotics, nitrous oxide, valproic acid, and cholestyramine)

Selenite is more quickly converted than selenate, through the mid-phase of selenide before making SeCys, while selenate needs to be first converted to selenite (54)

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