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Without any human safety data and tendon healing results that can be easily replicated with high-dose PRP, it would be medically irresponsible of me to do so

The mast cell reaction is an immune response that attempts to protect humans from pathogens

H 2 0 2 500 mol L 1 , which was used as a positive control, was added 15 min prior cell analysis

TLR signaling may promote calcification by activating the osteogenic differentiation pathway of VSMCs, with dendritic cells (DCs) being key responsive cells in the TLR pathway (75, 78)