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A 900 L aliquot of hypo-osmotic solution (prepared by dissolving 0.9 g fructose (Solarbio, #F8100, China) and 0.49 g sodium citrate (Solarbio, #S6100, China) in 100 mL deionized water) was pre-warmed at 37 C for 30 min in a constant temperature water bath

Hesperidin, at high doses, inhibits CYP1B1 and also CYP3a4

doi: 10.1002/mpo.10188 231 WuXZhangYPeiZChenSYangXChenYet al

SAC has been shown to decrease the levels of ROS and its neuroprotective effects are mediated predominantly through the caspase-12-dependent pathway in a concentration-dependent manner, but does not prevent the 4-hydroxynonenal-induced death of hippocampal neurons (32)