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While the spheroids treated with Ru(II)-OH or NP2 in a 1% O 2 atmosphere majorly consisted of living cells, the spheroids treated with NP4 in a 1% O 2 atmosphere consisted of dead cells (Fig

In this study, we successfully achieve tumor-targeted aggregation of an aggregation-induced emission photosensitizer (AIE-PS), TB m A, with the catalysis of a tumor-overexpressed enzyme, -Glutamyl Transferase (GGT)

Additionally, Ca 2+ involvement and the highly active mitochondrial oxidative phosphorylation processes in astrocytes and oligodendrocytes facilitate the substantial release of ROS

452 Targeted drug delivery Targeted drug delivery is a strategic approach in drug administration that aims to deliver therapeutic agents precisely to specific tissues or sites, thereby enhancing therapeutic efficacy while minimizing adverse reactions