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Why it matters: Short telomeres are associated with cellular senescence (aging) and disease

[DOI] [PubMed] [Google Scholar] 50.Hibuse T, Maeda N, Funahashi T, Yamamoto K, Nagasawa A, et al

Nature 569 , 723728 (2019)

The glutamate produced during the glutamine metabolism is further converted into -ketoglutarate (-KG) through glutamate dehydrogenase 1 (GLUD1), transaminases such as glutamate-oxaloacetate transaminase (GOT), glutamate-pyruvate transaminase (GPT), and phosphoserine transaminase (PSAT) and subsequently participates in the TCA cycle