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Sulfur-containing amino acid-related metabolic pathways, mainly including methionine, cysteine, and taurine, are characterized in macrophage polarization by the intersecting properties of methyl donor cycling-transsulfuration-redox homeostasis. Methionine (Met) not only serves as a substrate for protein synthesis within cells, but also generates SAM through the methionine cycle

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Descriptor-based Foundation Models for Molecular Property Prediction