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These tools enhance the predictive capacity of personalized nutrition frameworks and support the development of precision interventions for disease prevention and health optimization [16,17,18,19]

The first group considered at high risk for severe B12 deficiency had serum B12 287pmol/L and a median methylmalonic acid concentration of 120nmol/L, while the third group was classified as indeterminate and difficult to interpret with an intermediate serum B12 (126287pmol/L)

Furthermore, the levels of GSH decreased with increased oxidative stress markers in the HFD-fed mice, which reflect the exhaustion of antioxidant potential and increased oxidative stress

Contribution of the PI 3-kinase/Akt survival pathway toward osmotic preconditioning