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Autoantibodies, typically associated with autoimmune disorders, may contribute to tissue damage either directly or by forming immune complexes that deposit in tissues, triggering further inflammation (119)

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Courageous leaders like Governors Gary Juffa and Allan Bird, and MPs James Donald, Keith Iduhu, and James Nomane, have spoken out against this abuse

Improving the selectivity of covalent inhibitors is critical and can be optimized through various means, including adjusting the reactivity and reversibility of the electrophile (warhead), 571,572 non-covalent scaffolds, dosage, etc