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As a key energy substrate for tumor cells, Gln can be catabolized by glutaminase to generate -ketoglutarate (-KG), which directly enters the tricarboxylic acid (TCA) cycle [1]

In the following sections, we will discuss the nephroprotective effects and the underlying protective mechanisms of ALA in a variety of animal models of kidney injury, as indicated in Figure 1

It also has anti-inflammatory and immune-modulating properties, and studies show that having optimal vitamin C levels is essential for healthy lungs ( Vitamin C deficiency can significantly affect the immune system and may increase the risk of respiratory infection

Mobkl3 : Mobkl3 is both a member and a putative substrate of striatin family-protein phosphatase 2A (PP2A) complexes [33], an enzyme that belongs to a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling [34] which has been shown to participate in various signalling events crucially involved in neurodegenerative processes [35,36]