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American Journal of Hematology

648 Preclinical studies have shown that MSC transplantation improves nerve function and reduces neuropathic pain in diabetic animal models 649

It involves inflammation of the pancreas and can cause severe abdominal pain, nausea, and vomiting

IGF-I and -II had actions through the type 1 IGF receptor (IGF1R) demonstrated by Igf1r ko animals with 45% of wild type birth weight and no further effect when crossed with Igf1 ko animals