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However, conditional glutathione deficient mutants fail to adapt to intense heat waves or to induce thermomorphogenesis, suggesting that glutathione is involved in both heat adaptation mechanisms

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In humans, at least 11 functional isoforms of MTs are known, divided into four classes (MT-1 to MT-4), all of which contain twenty conserved cysteine residues that give them the ability to coordinate seven zinc ions (188, 189)

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