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Vagus nerve stimulation has been shown to improve cognitive processes and has been attributed to modulation of central noradrenergic and GABA systems, as well as neuronal adaptations within the amygdala, hippocampus, and prefrontal cortex (500)

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Inconsistent sleep patterns can disrupt the liver's ability to manufacture antioxidants

Unlike medication effects, which are usually aimed at altering action of one receptor or enzyme to ameliorate psychiatric symptoms [e.g., serotonergic pathway, glutamatergic pathway (57, 108)], the low glutamate diet aims to reduce glutamatergic excitotoxicity while concurrently increasing consumption of nutrients known to be protective against excitotoxicity, with the aim of improving neurotransmission (69, 109)