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(C) Activated microglia could also stimulate the endothelial expression of intracellular adhesion molecule 1 (ICAM1) from peripheral inflammatory pain stimulation, to alter the permeability of blood-brain barrier

The latest EUGOGO guidelines recommend a 6-month selenium supplementation for patients with mild and active TED of recent onset, because it improves eye manifestations and prevents progression to more severe forms [90]

demonstrated that the intravitreal injection of synthetic melanin-like nanoparticles can clear free radicals, with reduced ROS production in RPE cells, finally alleviate the vascular leakage and show the anti-angiogenic activity in an AMD-like model

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