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Although less well studied, cyanide does induce disruptions in metabolic pathways beyond inhibiting oxidative phosphorylation

The case of the 23-year-old woman who developed alopecia areata two months after starting semaglutide demonstrates that GLP-1 medications can potentially trigger autoimmune hair loss in susceptible individuals

In addition to these conventional sites of mitochondrial ROS generation, it has been recently reported that the branched-chain 2-oxoacid dehydrogenase (BCKDH) complex in mitochondria can produce superoxide and H 2 O 2 at higher rates than complex I from mitochondria (Quinlan et al., 2014)